In a combined effort between several U.S. institutions , new research into HIV fighting antibodies might find a way to stop the virus spreading.
The result of the 3 study teams testing might help scientists develop a new approach to handling the spread of AIDS or even stop the epidemic entirely.
The International AIDS Vaccine Initiative working with the Scripps Research Institute and the Rockefeller University , has published a new study in the journals Cells and Science.
The study focused on the use of immunogen proteins in order to help the body generate antibodies that are able to fight the human immunodeficiency virus.
Animal testing was done in order to see if immunogen proteins could as part of a molecular complex stimulate the immune system into producing neutralizing antibodies combating HIV.
The team used a protein called OD-GT8 60mer that activates the B cells which can fight of AIDS.
By using the protein on different animals, the scientist were able to observe the reactions in the body and test the way animal immune systems responded to the HIV virus.
The team observed as the test animal immune system started to neutralize the HIV strains when they were introduced into the body.
Usually vaccines are create by introducing a dormant or dead strain into the body, thus stimulating white cells to act and produce antibodies.
With HIV this classic technique does not work for multiple reasons, one being the fact that the virus is not quickly detected by the immune system because of the virus’s natural protein , meaning that it can take months until detection.
HIV strains also have a quick mutation cycle making it harder for the body to fight then if the virus was had a single stain.
If it will be approved for human testing and will be successful the new vaccine could prevent the spread of HIV, which in some countries on the African continent is endemic.
However it is not yet known if the new methods are usable in a cure as well. This leaves millions that have been already infected with no foreseeable curing treatment.
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